Risk factors of vaginal cuff infection in women undergoing laparoscopic hysterectomy for benign gynecological diseases

Aim This study aimed to identify the risk factors for vaginal cuff infection after laparoscopic hysterectomy benign gynecological diseases. Methods We conducted a retrospective cohort among 1559 Japanese women who underwent total (TLH) indications between 2014 and 2018 at Teine Keijinkai Hospital in Sapporo, Japan. All patients received preoperative antibiotics based on appropriate timing, choice, weight-based dosing. assessed of TLH, including demographic clinical variables, patient- surgery-related factors, using univariable multivariable logistic regression analyses. Results Among all 71 cases infections (4.6%) were recorded. Univariate analyses showed that current smoking, pathological result adenomyosis, use Seprafilm as an antiadhesive material, white blood cell counts postoperative day (POD) 2, C-reactive protein (CRP) level POD2 hematoma significantly associated with increased infection. In multivariate analysis, seprafilm, CRP Conclusion Current identified significant 30 days surgery TLH indications.